Targeting FOXO3a and sirtuins in breast cancer
SIRT proteins play an important role in the survival and drug resistance of tumour cells, especially during chemotherapy. In this study, we investigated the potency, specificity and cellular targets of three recently identified SIRT inhibitors, Sirtinol, Salermide and EX527. Our results identify the...
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Imperial College London
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.530258 |