Exploring the structure, function & regulation of the human glucagon-like peptide-1 receptor

Glucagon-like peptide-1 (GLP-1) enhances glucose-dependent insulin secretion and promotes β-cell function via its receptor (GLP-1R), which therefore is a validated target for the treatment of type 2 diabetes. Due to difficulties with peptide therapeutics, it is important to find small-molecule GLP-1...

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Bibliographic Details
Main Author: Huang, Yan
Other Authors: Willars, Gary ; Wilkinson, Graeme
Published: University of Leicester 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.530551