Human urotensin-II receptor desensitisation

Human Urotensin-II (U-II) is a cyclic undecapeptide that binds to the U-II receptor UT. The desensitisation mechanisms of the UT receptor (G_{q/11} coupled GPCR) are not well defined and hampered by (1) lack of native (in-vitro) models; (2) paucity of ligands, especially non-peptides and (3) irrever...

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Bibliographic Details
Main Author: Batuwangala, Madura Suharshana
Other Authors: Lambert, D.
Published: University of Leicester 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.530555