Studies on the effect of asparaginase in paediatric leukaemia
Asparaginase, an important agent in the treatment of acute lymphoblastic leukaemia, is thought to cause cell death by depriving lymphoblasts of asparagine. However, because asparaginase also hydrolyses glutamine, a critical fuel for normal lymphocyte function, the mechanism of asparaginase action re...
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University of Salford
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.535486 |