Altered expression of ion channels in hyperinsulinism

The ability of the pancreatic β-cell to secrete insulin in response to changes in glucose concentration is the cornerstone of glucose homeostasis. The β-cell couples glucose metabolism to electrical activity via the modulation of ion channel activity. Defects in β-cell ion channels can result in the...

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Bibliographic Details
Main Author: Adams, Leon
Other Authors: Dunne, Mark
Published: University of Manchester 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538515