What is the function of the ANKH protein in the kidney?
Pyrophosphate (PPi) has been known since the 1960s as an inhibitor of calcium renal stone formation. Naturally occurring mutations in a putative PPi transporter, ANK, causes renal calcification in mice. We hypothesised that the human homologue, ANKH, plays a role in PPi transport in the human kidney...
Main Author: | |
---|---|
Published: |
University of Newcastle Upon Tyne
2010
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.539080 |