Molecular genetic analysis of uveal melanoma

Uveal melanoma (UM) is the most common intraocular malignancy in adults. Approximately 40-50% of UM are fatal as a result of metastatic disease, usually occurring to the liver. Monosomy 3 and gains of chromosome 8q are the strongest genetic predictors of the metastatic disease. Initially, routine ge...

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Bibliographic Details
Main Author: Dopierala, Justyna Agnieszka
Published: University of Liverpool 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.539742