The binding and activation of the glucagon-like peptide-1 receptor by exendin-4

Background and purpose Exendin-4 (EX4) has the same physiological properties as glucagon-like peptide-1 (7-36)amide (GLP-1). EX4 has 50% identity with GLP-1, with an extra nine amino acids at its C-terminus. The two peptides mediate their functions through coupling to the glucagon like peptide-1 rec...

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Bibliographic Details
Main Author: Nasr, Elsayed Mohammed Nasr
Other Authors: Donnelly, D.
Published: University of Leeds 2010
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.540202