The role of MLL/AF4 in leukaemic cell biology
T(4;11) acute lymphoblastic leukaemia (ALL) presenting the fusion gene MLL/AF4 is a hallmark of infant ALL. The 5 year event free survival is less than 40%. It was shown that MLL/AF4 is important for cell cycle progression, proliferation, clonogenicity, engraftment in mice and repression of apoptosi...
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University of Newcastle Upon Tyne
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.542217 |