Design and synthesis of new modulators of liver receptor homologue-1

Nuclear receptor (NR) liver receptor homologue-1 (LRH-1) is a potential target for the treatment of breast cancers as a consequence of its regulation of aromatase and the estrogen receptor (ER). Development of modulators of NRs historically focuses on production of high affinity small molecules that...

Full description

Bibliographic Details
Main Author: Bayly, Andrew Robert
Other Authors: Spivey, Alan
Published: Imperial College London 2011
Subjects:
615
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.543365