Pif1- and Exo1-dependent nucleases coordinate resection at uncapped telomeres
Telomeres are present at the ends of most eukaryotic chromosomes and are bound by specialized telomere ‘capping’ proteins, preventing them from initiating a DNA Damage Response and cell cycle arrest analogous to that triggered by DNA Double Strand Breaks (DSBs). Resection of ‘uncapped’ telomeres and...
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University of Newcastle Upon Tyne
2011
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.544202 |