Pif1- and Exo1-dependent nucleases coordinate resection at uncapped telomeres

Telomeres are present at the ends of most eukaryotic chromosomes and are bound by specialized telomere ‘capping’ proteins, preventing them from initiating a DNA Damage Response and cell cycle arrest analogous to that triggered by DNA Double Strand Breaks (DSBs). Resection of ‘uncapped’ telomeres and...

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Bibliographic Details
Main Author: Dewar, James Michael
Published: University of Newcastle Upon Tyne 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.544202