Identification and characterisation of genes that confer susceptibility to childhood embryonal tumours
Wilms tumour is a childhood kidney tumour with an incidence of I in 10,000. I investigated a child with bilateral, young-onset Wilms tumour and a de novo 5:6)(q2l;q2l) translocation. Next generation sequencing localized the breakpoints to within 1.7 kb. Using long-range PCR, I identified that HACEI...
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Institute of Cancer Research (University Of London)
2011
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.546060 |