Identification and characterisation of genes that confer susceptibility to childhood embryonal tumours

Wilms tumour is a childhood kidney tumour with an incidence of I in 10,000. I investigated a child with bilateral, young-onset Wilms tumour and a de novo 5:6)(q2l;q2l) translocation. Next generation sequencing localized the breakpoints to within 1.7 kb. Using long-range PCR, I identified that HACEI...

Full description

Bibliographic Details
Main Author: Slade, Ingrid
Published: Institute of Cancer Research (University Of London) 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.546060