Structural and functional characterisation of conventional kinesin and mitotic kinesin Eg5 — a validated target for cancer chemotherapy

Kinesins are molecular motors that use energy from ATP hydrolysis to transport cargoes along microtubule tracks. There are at least 14 families of kinesins with different structural organisations but all kinesins have a motor domain that is the catalytic core for ATP hydrolysis and the binding site...

Full description

Bibliographic Details
Main Author: Kaan, Hung Yi Kristal
Published: University of Glasgow 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.547202