Identifying a role for Ciz1 in the DNA damage response

In proliferating cells, cell cycle arrest and DNA repair are induced upon detection of DNA damage. The DNA damage response (DDR) to double strand DNA breaks is mediated by phosphatidylinositol 3-kinase-like protein kinases (PIKKs), which propagate DDR signalling by phosphorylating SQ/TQ motifs in su...

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Bibliographic Details
Main Author: Roper, Katherine
Other Authors: Coverley, Dawn
Published: University of York 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.547339