Regulation of TGFβ-activated-kinase 1 (TAK1) in nuclear factor-κB and tumour necrosis factor/Eiger signalling in Drosophila melanogaster

Drosophila TGFbeta-Activating-Kinase 1 (dTAK1) is an essential component of both the Immune Deficiency (IMD) innate immune and TNF/Eiger apoptotic cascades. The IMD and JNK pathways bifurcate at the level of dTAK1. Hence, elucidating the regulatory mechanism of dTAK1 is pertinent to understanding th...

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Bibliographic Details
Main Author: Fernando, Merennege Dilan Anush
Other Authors: Ligoxygakis, Petros
Published: University of Oxford 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.547591