Novel antibiotics from DNA adenine methyltransferase inhibitors
DNA adenine methylation plays a role in several core bacterial processes, including DNA mismatch repair, the timing of DNA replication and gene expression. The dependence of bacterial virulence on the activity of Dam, an adenine methyltransferase, makes it an attractive target for novel antibiotics....
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University of Southampton
2009
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.548212 |