Assessment of algorithms for the prediction of metabolic drug-drug interactions
The aim of this work was to assess the ability of the static and dynamic (incorporating the time-course of the inhibitor) prediction models to predict drug-drug interactions (DDIs) using a population-based ADME simulator (Simcyp). This analysis focused on fluconazole, ketoconazole, itraconazole, flu...
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University of Manchester
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.549328 |