The role of A-Type lamins and LAP2a in cellular ageing of human fibroblasts in vitro

Mutations in LMNA gene have been linked to a number of age-related tissue-specific diseases and premature ageing syndromes termed laminopathies. The finding that A- type lamins affect longevity and maintenance of a number of somatic tissues makes them potential candidates in ageing of normal tissues...

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Bibliographic Details
Main Author: Pekovic, Vanja
Published: Durham University 2005
Subjects:
612
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.550091