The role of oxidative and nitrative stress and histone de-acetylation in rhinovirus induced acute exacerbations of Chronic Obstructive Pulmonary Disease

Acute exacerbations are the major cause of morbidity and mortality in COPD and respiratory virus infection is believed to be a leading aetiology. However mechanisms by which viruses induce acute exacerbations are poorly understood. This study reports the experimental inoculation with rhinovirus (RV)...

Full description

Bibliographic Details
Main Author: Footitt, Joseph
Other Authors: Adcock, Ian ; Mallia, Patrick ; Johnston, Sebastian
Published: Imperial College London 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.550936