Mechanisms, obstacles and opportunities of artificially enveloped adenovirus for safe and efficient gene delivery
Gene therapy with human adenovirus type S (AdS) has been extensively explored for the treatment of diseases resistant to traditional therapies. Following intravenous administration, Ad is rapidly cleared from systemic blood circulation with a half life of 2 minutes, and more than 99 % of the injecte...
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University College London (University of London)
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.550964 |