The role of Syntaxin 11 and the GTPases Rab7 and Arl8b in natural killer cell secretory lysosome exocytosis
Natural killer (NK) cells kill abnormal cells through the exocytosis of secretory lysosomes containing the cytotoxic proteins perforin and granzymes. Secretory lysosome exocytosis requires the movement of secretory lysosomes along microtubules to cluster at the microtubule organising centre (MTOC),...
| Main Author: | |
|---|---|
| Published: |
University of Leeds
2010
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.551471 |