Activity of endogenous L1 retrotransposons in human embryonal cells

Recent high throughput studies have led to the discovery of de novo L1 retrotransposition in malignant somatic cells, as well as large numbers of novel insertions, many of which are highly active in cell culture assays. These data suggest that L1 elements are robustly active, undergoing extensive di...

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Bibliographic Details
Main Author: Rahbari, Raheleh
Other Authors: Badge, Richard
Published: University of Leicester 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.551717