The identification and characterisation of novel proteins and metabolic signalling pathways that regulate TRAIL-induced apoptosis
TNF-related apoptosis inducing ligand (TRAIL) is a putative anti-cancer cytokine that is relatively specific for transformed cells however Mantle Cell Lymphoma (MCL) is resistant. TRAIL induces apoptosis through formation of a Death-Inducing Signalling Complex (DISC) and the successive activation of...
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University of Leicester
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.551738 |