A comparison of the pore-forming subunits of the ATP-sensitive potassium channel

Kir6.1 and Kir6.2 display several key differences in characteristics e.g. Kir6.2 can open spontaneously upon removal of inhibitory nucleotides while Kir6.1 cannot. Residues responsible for some of these disparate properties have been mapped to the N-terminus of Kir6.0. Mutant cDNAs for these subunit...

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Bibliographic Details
Main Author: Chadburn, Andrew James
Other Authors: Lodwick, Dave
Published: University of Leicester 2010
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.551896