Analysis of the developmental and physiological roles of histone deacetylases 1 and 2
Histone deacetylases (HDAC) 1 and 2 are highly similar enzymes that help regulate chromatin structure as the core catalytic components of co-repressor complexes. Although tissue specific deletion of HDAC1 and HDAC2 has demonstrated functional redundancy, germline deletion of HDAC1 in the mouse cause...
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University of Leicester
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.551921 |