Tools for probing 2A sequence space

Foot-and-mouth disease virus (FMDV) 2A is an oligopeptide composed of only 18 amino acids that can mediate a co-translational cleavage at its own C- terminus. It has been observed that 2A sequences do not show cleavage activity within bacterial organisms. Why 2A lacks activity in a prokaryotic organ...

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Bibliographic Details
Main Author: Escuin Ordinas, Helena
Other Authors: Ryan, Martin D.
Published: University of St Andrews 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.552238