Investigating agonist induced receptor conformational changes on the adenosine A2a receptor

G-protein coupled receptors (GPCRs) are one of the main targets for drug design. GPCR pharmaceutical research has bottlenecked on drug research, and the current assay systems are not creating therapeutic drugs from drug hits. The principal aim of this project was to establish a relationship between...

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Bibliographic Details
Main Author: Hedley, Diana
Published: University of Reading 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.553235