The biology of GPR50, the melatonin-related receptor

GPR50 is the mammalian ortholog of the avian/amphibian melatonin receptor, Mel1c, yet its ligand and physiological function remain unknown. Previous studies implicate the receptor in the control of energy homeostasis; Gpr50-/- mice demonstrate elevated basal metabolic rate, reduced fat stores, and p...

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Bibliographic Details
Main Author: Hand, Laura
Other Authors: Loudon, Andrew; Luckman, Simon
Published: University of Manchester 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.553451