Engineering and characterisation of novel protein covalent linkages in horseradish peroxidase (HRP) : effect on structure and function

Both mammalian and bacterial peroxidases contain novel covalent linkages. In the former a sulfonium linkage to a critical Met residue is thought to modify the normal planarity of the haem affecting the functional properties. Following on from the work of Metcalfe et al., 2004 which showed that such...

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Bibliographic Details
Main Author: Al-Fartusie, Falah Sumoon Daghal
Published: University of Sussex 2011
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.554548