On genetic variants underlying common disease

Genome-wide association studies (GWAS) exploit the correlation in ge- netic diversity along chromosomes in order to detect effects on disease risk without having to type causal loci directly. The inevitable downside of this approach is that, when the correlation between the marker and the causal var...

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Bibliographic Details
Main Author: Hechter, Eliana
Other Authors: Donnelly, Peter
Published: University of Oxford 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.555375