Development of anti-LMO2 drugs for treatment of T cell leukaemia
Dysregulation of the LM02 proto-oncogene as a result of reciprocal chromosomal translocation involving the T-cell receptor gene loci, is a hallmark of some cases of T-cell acute lymphoblastic leukaemia (T-ALLL an aggressive subset of leukaemia. Aberrant expression of the gene is also seen in a signi...
| Main Author: | |
|---|---|
| Published: |
University of Leeds
2011
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.555841 |