Role of suppressor of cytokine signalling 1 and 3 in rhinovirus infection in vitro and in vivo
Rhinovirus (RV) infection is responsible for most asthma exacerbations. Defective RV induced interferon (IFN)-β and IFN-λs has been observed in asthmatic bronchial epithelial cells (BECs). Suppressors of cytokine signalling (SOCS) are negative regulators of cytokine signalling including IFNs. This s...
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Imperial College London
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.555942 |