Pre-clinical metabolism studies with Fenretinide in paediatric cancer

Fenretinide (4-HPR) is a retinoic acid analogue used in clinical trials for the treatment of neuroblastoma and Ewing’s sarcoma. The work described involves investigations into factors that may impact on 4-HPR drug disposition. Metabolism of 4-HPR is of particular interest due to production of the ac...

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Bibliographic Details
Main Author: Illingworth, Nicola Ann
Published: University of Newcastle Upon Tyne 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.556036