A systems-based bottom-up mathematical modelling framework for investigating the effect of drugs on solid tumours

Understanding the effect of drugs on solid tumours presents a number of challenges owing to the complexity of the blood flow and drug transport, as well as the highly complex biochemical networks involved in the cellular response with characteristics of high non-linearity of signal transduction. It...

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Bibliographic Details
Main Author: Liu, Cong
Other Authors: Xu, Xiao ; Krishnan, J.
Published: Imperial College London 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.556529