Evaluating the use of chiral anthracene templates to access pyroglutamic acid

Approaches to prepare pyroglutamic acid derivatives using a chiral anthracene moiety have been carried out using a nucleophilic carboxylic acid synthon. A model study to prepare five membered ring lactams bearing a quaternary centre via a Ugi-3CR reaction using commercially available levulinic acid...

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Bibliographic Details
Main Author: Hasbullah, Siti Aishah Binti
Published: University of Sheffield 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.556737