Structure and activity of Clostridium botulinum neurotoxin functional fragments

Botulinum neurotoxins (BoNTs) cause flaccid paralysis by inhibiting neurotransmission at cholinergic nerve terminals. BoNTs consist of three essential domains for toxicity: the cell binding domain (Hc), the translocation domain (Hn) and the catalytic domain (LC). The binding function of the Hc domai...

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Bibliographic Details
Main Author: Masuyer, Geoffrey
Other Authors: Acharya, K-Ravi
Published: University of Bath 2012
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.557825