An investigation into the role of tumour cell loading on dendritic cell maturation

Introduction: Dendritic cells (DCs) have been extensively utilised in cancer immunotherapy due to their central role in immunity. Despite evident CTL reactivity, vaccination with peptide-pulsed DCs rarely achieved clinical benefits. Apoptotic tumour cells (TCs) are promising candidates for DC loadin...

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Bibliographic Details
Main Author: Kovalcsik, Edit
Published: St George's, University of London 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.558354