Structural and functional studies of Wnt signalling pathway antagonists
Wnt morphogens control embryonic development and adult tissue homeostasis. Deregulation of the Wnt signalling pathway leads to human diseases. This thesis covers work on two antagonists of the Wnt signalling pathway, Wnt inhibitory factor 1 (WIF-l) (Chapters 1 to 5) and secreted Frizzled-related pro...
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University of Oxford
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.558451 |