WNT signalling in joint repair and homeostasis

Disruption of the Wnt canonical signalling leads to the development of osteoarthritis both in human and in mice but the underlying molecular mechanisms are poorly understood. Both forced activation and blockade of Wnt/β catenin signalling lead to cartilage breakdown. This study attempts to unravel t...

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Bibliographic Details
Main Author: Nalesso, Giovanna
Published: Queen Mary, University of London 2011
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.558504