Investigation of ligand-induced conformational changes of the dopamine D2s receptor using fluorescence resonance energy transfer
Approximately 50 % of current pharmaceutical drugs target the G protein-coupled receptor (GPCR) family, rendering an understanding of the mechanisms behind their actions critical. Dopamine is a key neurotransmitter involved in motor function and behaviour and has been associated with disorders such...
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University of Reading
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.558734 |