Spatiotemporal dynamics of the DNA double strand break marker 53BP1 after exposure to ionising radiation

53BP1 is known to be involved in the DNA damage response and has been shown to localise into discrete foci at the site of DNA double strand breaks (DSBs) after exposure to ionising radiation (IR). Quantification of radiation induced foci (RIF) at varying times after exposure has been used to assess...

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Bibliographic Details
Main Author: McVean, Andrew
Other Authors: Anderson, R.
Published: Brunel University 2012
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.558994