Deregulation of the cell cycle by EBV nuclear antigens EBNA3A and EBNA3C
Cyclin-dependent kinase inhibitor p16INK4A is an important tumour suppressor and inducer of cellular senescence often inactivated during the development of cancer. I investigated the mechanism by which EBV latency-associated nuclear antigens EBNA3A and EBNA3C repress p16INK4A expression. Using lymph...
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Imperial College London
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.560639 |