Phospho-dependent modulation of potassium chloride co-transporter KCC2

The neuronal-specific potassium chloride co-transporter 2, KCC2, is a major chloride extruder in brain. The expression of KCC2 during neuronal development is fundamental to the switch of GABAergic response from excitatory to inhibitory. Malfunction of KCC2 can cause impairment of chloride homeostasi...

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Bibliographic Details
Main Author: Lee, H. C.
Published: University College London (University of London) 2009
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Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564659