The role of the NOD2 gene in the pathogenesis of Crohn's disease

Introduction: Crohn’s disease is characterised by an abnormal inflammatory response possibly induced by components of enteric bacteria, in genetically susceptible individuals. Mutations in the NOD2 gene are strongly associated with Crohn's disease, although the mechanisms by which these mutatio...

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Bibliographic Details
Main Author: Chalmers-Watson, T. A.
Published: University College London (University of London) 2009
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564762