The molecular pathogenesis of Huntington's disease
Huntington’s Disease (HD) is caused by an expansion in the CAG repeats of the huntingtin gene. This thesis describes an Ecdysone cell model which expressed inducible wild type (WT) and mutant (MT) N-terminal huntingtin (htt) in HEK 293 cells and constitutive EYFP full length (FL) htt in SH-SY5Y cell...
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University College London (University of London)
2009
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564778 |