Consequences of persistent antigen presentation following administration of HIV-1-derived lentiviral vectors
Lentiviral vectors (LVs) are promising tools for in vivo gene delivery, either to correct genetic defects or for vaccination. Intravenous administration of LVs results in stable transduction and expression of the transgene in antigen presenting cells (APCs) from the spleen. Therefore, it was decided...
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University College London (University of London)
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564838 |