Identification and characterisation of gene regulation by the POU4F3 (BRN-3C) transcription factor in the inner ear

Hair cells are the mechanosensory cells of the inner ear whose loss causes irreversible hearing loss in mammals. POU4F3, a POU-domain transcription factor, is only expressed in hair cells in the inner ear and is essential for hair cell terminal maturation in mice. In humans, it is essential for hair...

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Bibliographic Details
Main Author: Tornari, C.
Published: University College London (University of London) 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564927