Conditional mutagenesis in the immune system : targeting the expression of the iCre2 recombinase to neutrophils and macrophages

Conditional mutagenesis allows the introduction of tissue specific mutations in the mouse and is of crucial importance in converting genome sequence information into functional data for biomedical research. Mice expressing the Cre recombinase in a spatially controlled manner are essential in creatin...

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Bibliographic Details
Main Author: Könitzer, J. D.
Published: University College London (University of London) 2010
Subjects:
616
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564992