The role of Grb2 in FGFR2IIIc-mediated early signalling complexes
Receptor tyrosine kinases (RTKs) regulate cellular processes by undergoing autophosphorylation on their tyrosine residues upon ligand binding. Phosphotyrosine residues also provide binding sites for adaptor protein binding. Grb2 has been shown to play a role in RTK pathways by recruiting other signa...
Main Author: | |
---|---|
Published: |
University College London (University of London)
2011
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.565286 |