Chronic cytomegalovirus infection drives the accumulation of memory T cells with low functional avidity during ageing
Immune senescence is associated with a predisposition to infections, poor vaccination responses and early mortality in older individuals. Furthermore, evidence that chronic cytomegalovirus (CMV) infection is a key driver of immune senescence is becoming increasingly recognised. This thesis aimed to...
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University College London (University of London)
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.565392 |